COPD Medications: Master Pharmacology for Effective Treatment

Question 1

Which of the following is NOT a bronchodilator used to treat COPD?

Accepted Answer

Montelukast

Answer

Salmeterol

Answer

Ipratropium bromide

Answer

Tiotropium

Question 2

Which of the following is a long-acting beta2-agonist (LABA)?

Accepted Answer

Formoterol

Answer

Salbutamol

Answer

Ipratropium bromide

Answer

Tiotropium bromide

Question 3

What is the primary mechanism of action of inhaled corticosteroids (ICS)?

Accepted Answer

Reducing inflammation in the airways

Answer

Bronchospasm reversal

Answer

Increasing mucociliary clearance

Answer

Reducing airway hyperresponsiveness

Question 4

Which of the following is NOT an adverse effect of LABAs?

Accepted Answer

Bronchospasm

Answer

Tachycardia

Answer

Muscle cramps

Answer

Hypokalemia

Question 5

Which of the following mucolytics is used to treat purulent sputum in COPD?

Accepted Answer

Acetylcysteine

Answer

Ambroxol

Answer

Erdosteine

Answer

Guaifenesin

Question 6

Which of the following is not a characteristic of COPD?

Accepted Answer

Fully reversible airway disease

Answer

Progressive airflow limitation

Answer

Chronic cough

Answer

Airway inflammation

Question 7

What is the major mechanism of action of tiotropium bromide?

Accepted Answer

Competitive antagonism at muscarinic cholinoreceptors

Answer

Inhibition of phosphodiesterase-4

Answer

Stimulation of beta2-adrenoreceptors

Answer

Blockade of leukotriene receptors

Question 8

What is a contraindication for the use of inhaled anticholinergics in COPD?

Accepted Answer

Narrow-angle glaucoma

Answer

Prostatic hyperplasia

Question 9

Inhaled corticosteroids used in COPD primarily exert their therapeutic effect through:

Accepted Answer

Anti-inflammatory actions

Answer

Bronchodilation

Answer

Reduction of mucus production

Answer

Enhanced mucociliary clearance

Question 10

A defining characteristic of COPD is:

Accepted Answer

Progressive airflow limitation

Answer

Reversibility of airflow limitation

Answer

Bronchial hyperresponsiveness

Answer

Normal lung function

Question 11

Which mucolytic is exclusively indicated for the management of purulent sputum in cystic fibrosis?

Accepted Answer

Dornase alfa

Answer

Bromhexine

Answer

Carbocysteine

Answer

N-acetylcysteine

Question 12

Which factor does NOT contribute to the global rise in COPD cases?

Accepted Answer

Increased exercise

Answer

Air pollution

Answer

Smoking

Question 13

Which of the following is NOT a mechanism of action of bronchodilators?

Accepted Answer

Stimulation of mucus secretion

Answer

Relaxation of airway smooth muscle

Answer

Inhibition of acetylcholine release

Answer

Blockade of histamine receptors

Question 14

Which inhaled corticosteroid has the highest affinity for the glucocorticoid receptor?

Accepted Answer

Fluticasone

Answer

Budesonide

Answer

Salmeterol

Answer

Formoterol

Question 15

What is the primary adverse effect of long-acting muscarinic antagonists?

Accepted Answer

Tremor

Answer

Tachycardia

Answer

Hypoglycemia

Answer

Hepatotoxicity

Question 16

Which of the following is a phosphodiesterase 4 inhibitor?

Accepted Answer

Roflumilast

Answer

Salmeterol

Answer

Tiotropium

Answer

Montelukast

Question 17

What is the mechanism of action of mucolytics?

Accepted Answer

Reduction of mucus viscosity

Answer

Stimulation of mucus secretion

Answer

Inhibition of mucus production

Answer

Enhancement of ciliary function

Question 18

Which of the following is NOT an indication for the use of inhaled corticosteroids in COPD?

Accepted Answer

Reversal of airway obstruction

Answer

Prevention of exacerbations

Answer

Improvement of lung function

Answer

Reduction of inflammation

Question 19

Which of the following is a beta-2 agonist?

Accepted Answer

Salbutamol

Answer

Ipratropium

Answer

Montelukast

Answer

Nedocromil

Question 20

Which of the following is NOT a mechanism of action of inhaled corticosteroids in the management of COPD?

Accepted Answer

Bronchial smooth muscle relaxation

Answer

Improved mucociliary clearance

Answer

Inhibition of inflammatory cell migration

Answer

Reduction of airway inflammation

Question 21

Which of the following bronchodilators is a long-acting beta2-agonist (LABA)?

Accepted Answer

Salmeterol

Answer

Salbutamol

Answer

Ipratropium bromide

Question 22

Excessive mucus production is an indication for the use of which class of medications in COPD?

Accepted Answer

Mucolytics

Answer

Antibiotics

Answer

Bronchodilators

Answer

Inhaled corticosteroids

Question 23

Which of the following is a potential adverse effect of inhaled corticosteroids in COPD?

Accepted Answer

Oral candidiasis

Answer

Arrhythmias

Answer

Hypertension

Answer

Bronchospasm

Question 24

Which of the following is a contraindication to the use of long-acting beta2-agonists in COPD?

Accepted Answer

Uncontrolled arrhythmias

Answer

Asthma

Answer

Chronic bronchitis

Answer

Emphysema

Question 25

What is a key role of pulmonary rehabilitation in the management of COPD?

Accepted Answer

Improving exercise tolerance

Answer

Reducing inflammation

Answer

Preventing exacerbations

Answer

Reversing airway obstruction

Question 26

Which of the following is a key principle in the pharmacological management of COPD?

Accepted Answer

Regular use of controller medications

Answer

Avoidance of all respiratory irritants

Answer

Frequent use of antibiotics

Answer

Use of bronchodilators only when needed

Question 27

What is a potential benefit of using a combination inhaler in COPD?

Accepted Answer

Improved adherence to therapy

Answer

Lower overall cost

Answer

Increased bronchodilation

Answer

Reduced incidence of adverse effects

Question 28

Which of the following is a risk factor for the development of COPD?

Accepted Answer

Smoking

Answer

Hay fever

Answer

Obesity

Answer

Asthma