Drugs Used in Irritable Bowel Syndrome: Online Learning Quizzes

Question 1

Identify the antispasmodic that exhibits antimuscarinic activity.

Accepted Answer

Cimetropium

Answer

Alosetron

Answer

Trimebutine

Answer

Tegaserod

Question 2

Which mechanism underpins the primary action of bulk-forming laxatives?

Accepted Answer

Absorbing intestinal fluid to form a soft gel

Answer

Stimulating colonic contractions

Answer

Blocking sodium-potassium pumps

Answer

Promoting bile secretion

Question 3

Identify the antidiarrheal agent that exerts its effect by binding to opioid receptors in the gut.

Accepted Answer

Loperamide

Answer

Octreotide

Answer

Racecadotril

Answer

Eluxadoline

Question 4

Which of the following is a common adverse effect associated with antispasmodic use?

Accepted Answer

Constipation

Answer

Rapid heart rate

Answer

Diarrhea

Answer

Constriction of airways

Question 5

Which factor is NOT implicated in the pathophysiology of Irritable Bowel Syndrome (IBS)?

Accepted Answer

Impaired pancreatic function

Answer

Abnormal gastrointestinal motility

Answer

Increased sensitivity of the gut

Answer

Psychological stress

Question 6

For IBS with predominant constipation (IBS-C), which treatment option is typically recommended as first-line therapy?

Accepted Answer

Lactulose

Answer

Trimebutine

Answer

Loperamide

Answer

Alosetron

Question 7

Which condition represents a contraindication for the use of anticholinergic antispasmodics?

Accepted Answer

Glaucoma

Answer

Enlarged prostate

Answer

Rapid heart rate

Answer

Vomiting

Question 8

Identify a potential drug interaction associated with alosetron.

Accepted Answer

Warfarin

Answer

Paracetamol

Answer

Cimetidine

Answer

Omeprazole

Question 9

What is the primary role of psychological therapies in the management of IBS?

Accepted Answer

Reducing stress and enhancing coping mechanisms

Answer

Directly alleviating symptoms

Answer

Modifying dietary habits

Answer

Minimizing the need for pharmacological treatment

Question 10

Describe how the mechanism of action of antispasmodics aligns with their clinical efficacy in alleviating IBS symptoms.

Accepted Answer

Antispasmodics block smooth muscle contractions, reducing abdominal pain and discomfort associated with IBS.

Answer

Antispasmodics enhance intestinal motility, thereby speeding up the passage of stool and relieving constipation.

Answer

Antispasmodics possess anti-inflammatory properties, improving mucosal integrity and reducing diarrhea.

Answer

Antispasmodics have no direct impact on IBS symptoms and are not clinically beneficial in this condition.

Question 11

Which is a clinical use of laxatives in IBS?

Accepted Answer

Relieving constipation

Answer

Treating diarrhea

Answer

Preventing bloating

Answer

Reducing abdominal pain

Question 12

Which type of antidiarrheal agent acts by slowing intestinal motility?

Accepted Answer

Opioid agonists

Answer

Bulk-forming agents

Answer

Antimuscarinics

Answer

5-HT3 antagonists

Question 13

Which of the following is NOT a potential adverse effect of ibuprofen when used for IBS?

Accepted Answer

Blurred vision

Answer

Gastrointestinal bleeding

Answer

Headache

Answer

Constipation

Question 14

Which is a contraindication to the use of laxatives?

Accepted Answer

Bowel obstruction

Answer

Diarrhea

Answer

Abdominal pain

Answer

Constipation

Question 15

Which of the following drugs is an example of a 5-HT3 antagonist used as an antidiarrheal?

Accepted Answer

Ondansetron

Answer

Diphenoxylate

Answer

Loperamide

Answer

Polyethylene glycol

Question 16

Which statement about the use of antispasmodics in IBS is correct?

Accepted Answer

They are contraindicated in patients with glaucoma.

Answer

They are effective in reducing both diarrhea and constipation.

Answer

They can be used long-term without any significant adverse effects.

Answer

They have no impact on abdominal pain.

Question 17

In the management of IBS-D, which antispasmodic is considered most appropriate to alleviate abdominal pain and loose stools?

Accepted Answer

Hyoscine butylbromide

Answer

Metoclopramide

Answer

Domperidone

Question 18

When using loperamide for IBS-D, which patient education point is essential to reinforce?

Accepted Answer

Avoid prolonged use to prevent dependence.

Answer

Take loperamide with meals to reduce gastrointestinal distress.

Answer

Abstain from alcohol consumption, as it may worsen diarrhea.

Answer

Monitor blood pressure vigilantly for possible hypotension.

Question 19

Regarding dietary modifications in IBS management, which statement accurately reflects their significance?

Accepted Answer

Dietary modifications can assist in identifying and excluding trigger foods that exacerbate symptoms.

Answer

Dietary modifications offer a definitive cure for IBS.

Answer

Dietary modifications should only be considered after drug therapy proves ineffective.

Question 20

A patient taking hyoscine butylbromide and a stimulant laxative for IBS reports severe abdominal cramps. What is the most probable explanation?

Accepted Answer

The stimulant laxative may be enhancing the antispasmodic effect of hyoscine butylbromide.

Answer

Hyoscine butylbromide may be interacting with the laxative, resulting in increased gastrointestinal motility.

Answer

The patient may be experiencing an adverse effect of the antispasmodic.

Question 21

Which of the following is an atypical symptom of irritable bowel syndrome (IBS)?

Accepted Answer

Fever

Answer

Constipation or diarrhea

Answer

Abdominal pain

Answer

Bloating

Question 22

When providing patient education on bulking agents for IBS-C, which instruction is crucial to emphasize?

Accepted Answer

Increase fluid intake to prevent constipation.

Answer

Monitor blood pressure regularly for potential hypotension.

Answer

Refrain from alcohol consumption, as it can exacerbate constipation.

Answer

Avoid taking the bulking agent with food.