Master Gastrointestinal Disorders with Interactive Quizzes

Question 1

For adults with uncomplicated peptic ulcer disease, which of these is NOT a first-line treatment?

Accepted Answer

Amoxicillin

Answer

Proton pump inhibitors

Answer

Histamine-2 receptor antagonists

Answer

Sucralfate

Question 2

Identify the most severe complication potentially associated with inflammatory bowel disease:

Accepted Answer

Toxic megacolon

Answer

Ulceration and bleeding

Answer

Stricture formation

Answer

Bowel perforation

Question 3

What is the primary therapeutic goal in managing irritable bowel syndrome (IBS)?

Accepted Answer

Management and relief of symptoms

Answer

Complete remission of symptoms

Answer

Elimination of the underlying cause

Answer

Normalization of bowel movements

Question 4

What is the primary mechanism of action of octreotide in the management of diarrhoea?

Accepted Answer

Inhibition of gastrointestinal fluid secretion

Answer

Stimulation of intestinal motility

Answer

Enhancement of intestinal absorption

Answer

Neutralization of gastric acid

Question 5

Which potential adverse effect is associated with long-term proton pump inhibitor therapy?

Accepted Answer

Vitamin B12 malabsorption

Answer

Increased risk of gastric cancer

Answer

Gastric acid overproduction

Answer

Constipation

Question 6

For Crohn's disease, what is the preferred route of administration for infliximab?

Accepted Answer

Intravenous

Answer

Oral

Answer

Subcutaneous

Answer

Intramuscular

Question 7

Which of the following is NOT a common symptom of peptic ulcer disease?

Accepted Answer

Constipation

Answer

Epigastric pain

Answer

Heartburn

Answer

Nausea

Question 8

The first-line treatment for mild inflammatory bowel disease is:

Accepted Answer

5-aminosalicylic acid (5-ASA)

Answer

Corticosteroids

Answer

Immunomodulators

Answer

Biologics

Question 9

Which of the following is a mechanism of action of proton pump inhibitors?

Accepted Answer

Inhibition of gastric acid secretion

Answer

Neutralization of gastric acid

Answer

Enhancement of mucosal barrier function

Answer

Promotion of prostaglandin synthesis

Question 10

The primary pharmacological target of anticholinergics in the treatment of irritable bowel syndrome is:

Accepted Answer

Muscarinic receptors

Answer

Nicotinic receptors

Answer

Adrenergic receptors

Answer

Dopamine receptors

Question 11

The recommended duration of treatment for Helicobacter pylori infection is:

Accepted Answer

21 days

Answer

10 days

Answer

14 days

Answer

28 days

Question 12

Which of the following drugs is NOT used in the treatment of Crohn's disease?

Accepted Answer

Ranitidine

Answer

Azathioprine

Answer

Methotrexate

Answer

Sulfasalazine

Question 13

The primary pharmacological effect of opioids in the treatment of diarrhea is:

Accepted Answer

Reduction of intestinal motility

Answer

Inhibition of gastric acid secretion

Answer

Stimulation of water absorption

Answer

Enhancement of mucosal barrier function

Question 14

How should inflammatory bowel disease be managed long-term?

Accepted Answer

Maintain remission with medication, monitor for complications, and adjust medication as needed.

Answer

Treat symptoms as they arise, without monitoring.

Answer

Use antibiotics indefinitely to prevent recurrence.

Answer

Delay treatment until symptoms become severe.

Question 15

Which of the following are potential adverse effects of antispasmodics used to treat irritable bowel syndrome?

Accepted Answer

Constipation, dry mouth, urinary retention, and blurred vision

Answer

Diarrhea, increased salivation, urinary incontinence, and double vision

Answer

Nausea, vomiting, abdominal pain, and headache

Question 16

How do lifestyle modifications contribute to the management of gastrointestinal disorders?

Accepted Answer

They can improve adherence to prescribed medications.

Answer

They can completely replace pharmacological treatment.

Answer

They are only effective in minor cases.

Answer

They have no role in managing gastrointestinal disorders.

Question 17

Which of the following is **NOT** a typical clinical manifestation of inflammatory bowel disease?

Accepted Answer

Hematemesis

Answer

Intermittent diarrhea

Answer

Abdominal pain

Answer

Recurrent fever

Question 18

Which of the following therapeutic classes is **not commonly** used in the management of irritable bowel syndrome?

Accepted Answer

Opioid agonists

Answer

Antispasmodics

Answer

Antidepressants

Answer

Laxatives

Question 19

Classify H2 receptor antagonists based on their chemical structure and discuss their clinical implications.

Accepted Answer

Imidazoles (e.g., ranitidine) and non-imidazoles (e.g., famotidine)

Answer

Competitive and non-competitive H2 receptor antagonists

Answer

Reversible and irreversible H2 receptor antagonists

Question 20

Which medication is the first-line treatment for mild to moderate ulcerative colitis?

Accepted Answer

5-aminosalicylic acid (5-ASA)

Answer

Infliximab

Answer

Azathioprine

Answer

Budesonide

Question 21

Which is a characteristic symptom of gastroesophageal reflux disease (GORD)?

Accepted Answer

Heartburn

Answer

Constipation

Answer

Nausea

Answer

Diarrhea

Question 22

What is the primary mechanism of action of proton pump inhibitors (PPIs) in the treatment of peptic ulcer disease?

Accepted Answer

Inhibition of gastric acid secretion

Answer

Reduction of pepsin activity

Answer

Enhancement of gastric motility

Answer

Stimulation of gastric mucus production