Pharmacology of Adrenergic Agonists and Antagonists: Online Quizzes and Learning

Question 1

Identify the mechanism of action that is NOT associated with beta-adrenoceptor agonists:

Accepted Answer

Inhibition of phosphodiesterase

Answer

Activation of adenylyl cyclase

Answer

Stimulation of protein kinase A

Answer

Increase in intracellular cAMP levels

Question 2

Select the selective alpha-1 adrenoceptor antagonist from the options provided:

Accepted Answer

Terazosin

Answer

Phenoxybenzamine

Answer

Propranolol

Answer

Salmeterol

Question 3

Which receptor subtype mediates the vasopressor effects of adrenaline?

Accepted Answer

Alpha-1

Answer

Alpha-2

Answer

Beta-1

Answer

Beta-2

Question 4

Which of the following is **not** a mechanism of action of alpha-adrenergic agonists?

Accepted Answer

Bronchodilation

Answer

Vasoconstriction

Answer

Mydriasis

Answer

Hyperglycemia

Question 5

Which of the following is a common adverse effect of beta-blockers?

Accepted Answer

Bradycardia

Answer

Hypertension

Answer

Tachycardia

Answer

Bronchospasm

Question 6

Which of the following mechanisms is involved in the bronchodilatory effect of beta-2 adrenergic agonists?

Accepted Answer

Relaxation of bronchial smooth muscle

Answer

Increased secretion of mucus

Answer

Vasoconstriction of pulmonary arteries

Answer

Inhibition of mast cell degranulation

Question 7

Which of the following is NOT a classification of adrenergic receptors? Choose the answer that is different from the other three.

Accepted Answer

Dopaminergic

Answer

Alpha-1

Answer

Alpha-2

Answer

Beta-1

Question 8

The primary mechanism of action of alpha-1 adrenergic agonists involves:

Accepted Answer

Activation of phospholipase C

Answer

Inhibition of adenylate cyclase

Answer

Opening of potassium channels

Answer

Blockade of calcium channels

Question 9

Which of the following is a therapeutic use of beta-blockers?

Accepted Answer

Lowering blood pressure (Hypertension)

Answer

Relieving asthma symptoms

Answer

Treating Parkinson's disease

Answer

Managing schizophrenia

Question 10

The most common adverse effect linked to alpha-2 adrenergic agonists is:

Accepted Answer

Low blood pressure (Hypotension)

Answer

Rapid heart rate (Tachycardia)

Answer

Narrowing of airways (Bronchospasm)

Answer

High blood sugar levels (Hyperglycemia)

Question 11

Activation of which type of adrenergic receptor typically leads to vasoconstriction?

Accepted Answer

Alpha-1

Answer

Alpha-2

Answer

Beta-1

Answer

Beta-2

Question 12

The primary mechanism of action of beta-2 adrenergic agonists involves:

Accepted Answer

Activation of adenylate cyclase

Answer

Inhibition of phospholipase C

Answer

Opening of sodium channels

Answer

Blockade of potassium channels

Question 13

Which of the following is **not** a classification of adrenergic agonists?

Accepted Answer

Beta-1

Answer

Alpha-1

Answer

Alpha-2

Answer

Beta-2

Question 14

What is a common mechanism of action shared by both alpha- and beta-adrenoceptors?

Accepted Answer

G protein-coupled receptor activation

Answer

Ion channel modulation

Answer

Enzyme inhibition

Answer

DNA transcription regulation

Question 15

Which adverse effect is commonly associated with alpha-blockers?

Accepted Answer

Hypotension

Answer

Tachycardia

Answer

Bradycardia

Answer

Hypertension

Question 16

Which of the following drugs is an example of a non-selective alpha-blocker?

Accepted Answer

Phentolamine

Answer

Prazosin

Answer

Terazosin

Answer

Yohimbine

Question 17

Which mechanism is primarily responsible for the bronchodilatory effect of beta-2 agonists?

Accepted Answer

Inhibition of smooth muscle contraction

Answer

Stimulation of mucus secretion

Answer

Vasoconstriction

Answer

Bradycardia

Question 18

Which receptor subtype is primarily responsible for the vasoconstrictor effects of adrenergic agonists?

Accepted Answer

Alpha-1

Answer

Alpha-2

Answer

Beta-1

Answer

Beta-2

Question 19

What is a primary mechanism of action of dopamine antagonists?

Accepted Answer

Blockade of dopamine D2 receptors

Answer

Inhibition of dopamine synthesis

Answer

Stimulation of dopamine release

Answer

Enhancement of dopamine reuptake

Question 20

Indirect-acting sympathomimetics enhance the effects of norepinephrine by which mechanism?

Accepted Answer

Blocking norepinephrine reuptake

Answer

Stimulating alpha-1 receptors

Answer

Activating beta-2 receptors

Question 21

A patient presents with hypertension. Which of the following adrenergic antagonists would be most appropriate for treating this condition?

Accepted Answer

Atenolol (a selective β1-blocker)

Answer

Phenylephrine (an α1-agonist)

Answer

Isoproterenol (a non-selective β-agonist)

Answer

Salbutamol (a β2-agonist)

Question 22

Which of the following is a characteristic effect of α1-adrenergic receptor activation?

Accepted Answer

Vasoconstriction of blood vessels

Answer

Lowering of blood pressure

Answer

Bronchodilation of airways

Answer

Increase in heart rate

Question 23

A patient with asthma is prescribed medication to relieve bronchospasm. Which of the following is most likely to be prescribed?

Accepted Answer

Salbutamol (a selective β2-agonist)

Answer

Clonidine (an α2-agonist)

Answer

Phenoxybenzamine (an α1-blocker)

Answer

Propranolol (a non-selective β-blocker)

Question 24

Which of the following adrenergic agonists is commonly used to treat nasal congestion?

Accepted Answer

Pseudoephedrine (an α1-agonist)

Answer

Albuterol (a β2-agonist)

Answer

Dobutamine (a β1-agonist)

Answer

Clonidine (an α2-agonist)

Question 25

A patient taking a non-selective β-blocker experiences bradycardia and bronchospasm. Which of the following is the most likely explanation?

Accepted Answer

Non-selective blockade of both β1 and β2 receptors

Answer

High dose of medication

Answer

Allergic reaction to the medication

Answer

Pre-existing condition exacerbating the effects of the medication

Question 26

Which of the following adverse effects is commonly associated with α1-adrenergic antagonists?

Accepted Answer

Orthostatic hypotension

Answer

Bradycardia

Answer

Bronchospasm

Answer

Increased blood pressure

Question 27

Which of the following adrenergic agonists is used in the treatment of heart failure?

Accepted Answer

Dobutamine (a β1-agonist)

Answer

Phenylephrine (an α1-agonist)

Answer

Salmeterol (a long-acting β2-agonist)

Answer

Clonidine (an α2-agonist)

Question 28

A patient with glaucoma is prescribed a medication to reduce intraocular pressure. Which of the following is most likely to be prescribed?

Accepted Answer

Timolol (a non-selective β-blocker)

Answer

Albuterol (a β2-agonist)

Answer

Dobutamine (a β1-agonist)

Answer

Phenylephrine (an α1-agonist)

Question 29

Which of the following statements correctly describes the mechanism of action of β2-adrenergic agonists in treating asthma?

Accepted Answer

Stimulation of β2 receptors in the bronchioles, leading to smooth muscle relaxation and bronchodilation

Answer

Inhibition of the release of histamine and other inflammatory mediators

Question 30

Which of the following is an example of a selective β1-blocker?

Accepted Answer

Metoprolol

Answer

Timolol

Answer

Nadolol

Answer

Propranolol