Antipsychotic Drugs Pharmacology: Learn and Test Your Knowledge

Question 1

Which of the following medications is classified as an atypical antipsychotic drug?

Accepted Answer

Risperidone

Answer

Chlorpromazine

Answer

Haloperidol

Answer

Fluphenazine

Question 2

What is the primary mechanism of action of typical antipsychotic drugs?

Accepted Answer

Antagonism of dopamine D2 receptors

Answer

Enhancement of serotonin reuptake

Answer

Inhibition of acetylcholinesterase

Answer

Stimulation of NMDA receptors

Question 3

Which of the following is a common therapeutic use of antipsychotic drugs?

Accepted Answer

Schizophrenia

Answer

Depression

Answer

Epilepsy

Answer

Parkinson's disease

Question 4

Which of the following atypical antipsychotic drugs is commonly used to treat refractory schizophrenia?

Accepted Answer

Clozapine

Answer

Olanzapine

Answer

Risperidone

Answer

Quetiapine

Question 5

A patient taking an atypical antipsychotic medication has developed tardive dyskinesia. Which of the following management strategies is most appropriate?

Accepted Answer

Switch to a different antipsychotic drug with a lower propensity for causing EPS, such as clozapine

Answer

Increase the dose of the antipsychotic drug

Answer

Prescribe an anticholinergic drug

Answer

Stop the antipsychotic drug

Question 6

What is the primary mechanism of action of conventional (typical) antipsychotics?

Accepted Answer

Antagonism at dopamine D2 receptors

Answer

Antagonism at serotonin 5-HT2A receptors

Answer

Inhibition of norepinephrine reuptake

Answer

Potentiation of GABAergic neurotransmission

Question 7

Which of the following atypical antipsychotics has a high affinity for both dopamine D2 and serotonin 5-HT2A receptors?

Accepted Answer

Olanzapine

Answer

Clozapine

Answer

Quetiapine

Answer

Risperidone

Question 8

The primary mechanism of action of typical antipsychotics is:

Accepted Answer

Dopamine D2 receptor blockade

Answer

Serotonin reuptake inhibition

Answer

Acetylcholine potentiation

Answer

GABA antagonism

Question 9

An example of an atypical antipsychotic is:

Accepted Answer

Clozapine

Answer

Chlorpromazine

Answer

Haloperidol

Answer

Thiothixene

Question 10

Antipsychotic drugs are primarily used to treat:

Accepted Answer

Schizophrenia

Answer

Mania

Answer

Autism spectrum disorders

Answer

Obsessive-compulsive disorder

Question 11

Which of the following is NOT a typical antipsychotic drug?

Accepted Answer

Risperidone

Answer

Haloperidol

Answer

Chlorpromazine

Answer

Thioridazine

Question 12

What is the primary mechanism of action of typical antipsychotics?

Accepted Answer

Dopamine D2 receptor blockade

Answer

Acetylcholine muscarinic receptor blockade

Answer

Noradrenaline α1 receptor blockade

Answer

Serotonin 5-HT2A receptor blockade

Question 13

What does the term 'depot injection' refer to?

Accepted Answer

A form of antipsychotic medication that is administered intramuscularly and provides sustained release

Answer

A type of antipsychotic medication that is used for treating acute psychotic episodes

Answer

A form of antipsychotic medication that is administered intravenously

Answer

A form of antipsychotic medication that is administered orally

Question 14

In the management of schizophrenia, how do antipsychotic drugs complement other therapeutic modalities and psychosocial interventions?

Accepted Answer

Antipsychotic drugs should be combined with other therapies and psychosocial interventions for optimal outcomes.

Answer

Antipsychotic drugs are the only necessary treatment for schizophrenia.

Answer

Antipsychotic drugs solely address the positive symptoms of schizophrenia.

Answer

Antipsychotic drugs can fully cure schizophrenia, eliminating all symptoms and impairments.

Question 15

What is the main pharmacological mechanism of action of typical antipsychotics?

Accepted Answer

Dopamine D2 receptor blockade

Answer

Acetylcholine muscarinic receptor inhibition

Answer

Serotonin 5-HT2A receptor antagonism

Answer

Glutamate NMDA receptor potentiation

Question 16

Which of the following atypical antipsychotics has the strongest affinity for serotonin 5-HT2A receptors?

Accepted Answer

Clozapine

Answer

Risperidone

Answer

Quetiapine

Answer

Olanzapine

Question 17

What is a common indication for the use of antipsychotics?

Accepted Answer

Schizophrenia

Answer

Dementia

Answer

Anxiety

Answer

Depression

Question 18

Which of the following is an example of a long-acting injectable antipsychotic drug?

Accepted Answer

Risperidone consta

Answer

Olanzapine

Answer

Quetiapine

Answer

Clozapine

Question 19

Which of the following is NOT a classification of antipsychotic drugs?

Accepted Answer

Tricyclic antidepressants

Answer

Second-generation

Answer

Typical

Answer

Atypical

Question 20

Which of the following is the main mechanism of action of typical antipsychotics?

Accepted Answer

Dopamine D2 receptor blockade

Answer

Norepinephrine reuptake inhibition

Answer

Acetylcholine receptor blockade

Answer

Serotonin reuptake inhibition

Question 21

Which of the following is an example of an atypical antipsychotic drug?

Accepted Answer

Clozapine

Answer

Fluphenazine

Answer

Chlorpromazine

Answer

Haloperidol

Question 22

What is a primary therapeutic use of antipsychotic drugs?

Accepted Answer

Treatment of schizophrenia

Answer

Management of anxiety disorders

Answer

Prevention of seizures

Answer

Relief of pain

Question 23

Which of the following is a potential adverse effect associated with antipsychotic drugs?

Accepted Answer

Tardive dyskinesia

Answer

Hypertension

Answer

Bradycardia

Answer

Bronchitis

Question 24

Which of the following statements about the pharmacology of antipsychotic drugs is accurate?

Accepted Answer

Atypical antipsychotics have a broader receptor profile compared to typical antipsychotics.

Answer

Antipsychotics are effective for all forms of mental illness.

Answer

All antipsychotics cause significant sedation.

Question 25

Which of the following is a known risk factor for developing tardive dyskinesia?

Accepted Answer

Long-term use of high doses of typical antipsychotics

Answer

Young age at first exposure to antipsychotics

Answer

Use of atypical antipsychotics

Question 26

Which of the following statements about the use of antipsychotic drugs in pregnancy is true?

Accepted Answer

Antipsychotic drugs should be avoided in the first trimester of pregnancy.

Answer

Antipsychotic drugs are safe to use throughout pregnancy.

Answer

All antipsychotic drugs are teratogenic.