Humoral and Cell-Mediated Immunity: Interactive Learning Quizzes

Question 1

Which of the following is NOT a function of antibodies in humoral immunity?

Accepted Answer

Producing cytokines

Answer

Neutralizing microorganisms

Answer

Activating the complement cascade

Answer

Promoting phagocytosis

Question 2

What factor determines a pathogen's ability to be recognized by B cells?

Accepted Answer

Antigenicity

Answer

Infectivity

Answer

Virulence

Question 3

How does the inflammatory response usually resolve after an infection or tissue damage?

Accepted Answer

Anti-inflammatory cytokines are released to reduce the immune response.

Answer

Phagocytes destroy all pathogens or damaged tissue, ending inflammation.

Answer

The immune system eventually runs out of resources and can't keep up the inflammation.

Answer

Unresolved inflammation always leads to chronic disease.

Question 4

Which of the following accurately describes a key characteristic of humoral immunity?

Accepted Answer

It involves the production of antibodies by B cells.

Answer

It offers protection against intracellular pathogens.

Answer

It is mediated by T lymphocytes.

Answer

It confers long-term immunological memory.

Question 5

Which type of T cell has the primary function of directly eliminating infected cells?

Accepted Answer

Cytotoxic T cells

Answer

Helper T cells

Answer

Suppressor T cells

Answer

Memory T cells

Question 6

What is the primary function of cytokines within the immune system?

Accepted Answer

To activate and differentiate immune cells

Answer

To directly destroy pathogens

Answer

To form physical barriers against infection

Answer

To store immunological memory

Question 7

What is the primary responsibility of the major histocompatibility complex (MHC)?

Accepted Answer

Presenting antigens to T cells

Answer

Producing antibodies

Answer

Killing infected cells

Answer

Activating B cells

Question 8

Which of the following accurately characterizes a primary immune response?

Accepted Answer

It is generally slower and less effective compared to a secondary response.

Answer

It involves the activation of memory T and B cells.

Answer

It produces a significant amount of antibodies.

Answer

It provides long-term immunity.

Question 9

What is the primary role of dendritic cells in the immune system?

Accepted Answer

Presenting antigens to T cells

Answer

Producing cytokines

Answer

Killing infected cells

Answer

Producing antibodies

Question 10

Which of the following is considered a type of innate immune response?

Accepted Answer

Complement activation

Answer

Antibody-mediated immunity

Answer

Cell-mediated immunity

Answer

Immunological memory

Question 11

What is the primary function of the thymus gland in the immune system?

Accepted Answer

Maturing T cells

Answer

Producing B cells

Answer

Producing antibodies

Answer

Storing immunological memory

Question 12

What is a key function of B cells in the immune response?

Accepted Answer

Produce antibodies

Answer

Engulf and destroy pathogens

Answer

Release cytotoxic molecules

Answer

Activate complement

Question 13

Which type of T cell plays a crucial role in destroying cells infected with intracellular pathogens?

Accepted Answer

Cytotoxic T cells (Tc)

Answer

Helper T cells (Th)

Answer

Regulatory T cells (Treg)

Answer

Memory T cells

Question 14

Which cytokine is primarily responsible for stimulating the proliferation and differentiation of B cells?

Accepted Answer

Interleukin-4 (IL-4)

Answer

Interferon-gamma (IFN-γ)

Answer

Interleukin-10 (IL-10)

Answer

Tumor Necrosis Factor-alpha (TNF-α)

Question 15

Which of the following mechanisms is NOT involved in antibody-mediated neutralization of pathogens?

Accepted Answer

Antibody-dependent cell-mediated cytotoxicity (ADCC)

Answer

Opsonization

Answer

Complement activation

Answer

Agglutination

Question 16

Which type of hypersensitivity reaction is characterized by the sudden release of histamine and other inflammatory mediators, causing immediate symptoms?

Accepted Answer

Type I

Answer

Type II

Answer

Type III

Answer

Type IV

Question 17

Which type of vaccine is designed to induce both antibody-mediated and cell-mediated immune responses?

Accepted Answer

Live attenuated vaccine

Answer

Inactivated vaccine

Answer

Subunit vaccine

Answer

Toxoid vaccine

Question 18

Which cell type is primarily responsible for presenting antigens to T cells, initiating the adaptive immune response?

Accepted Answer

Dendritic cells

Answer

Macrophages

Answer

Neutrophils

Answer

B cells

Question 19

Which immune deficiency disorder is primarily characterized by a lack of functional T cells, leading to severe immunodeficiency?

Accepted Answer

Severe combined immunodeficiency (SCID)

Answer

X-linked agammaglobulinemia (XLA)

Answer

DiGeorge syndrome

Answer

Wiskott-Aldrich syndrome

Question 20

Which of the following is **NOT** a function of antibodies?

Accepted Answer

Directly kill pathogens

Answer

Activate complement

Answer

Neutralize toxins

Answer

Opsonize pathogens

Question 21

Which cell type is primarily responsible for presenting antigens to T cells?

Accepted Answer

Antigen-presenting cell

Answer

B cell

Answer

Natural killer cell

Answer

T cell

Question 22

Which cytokine is **primarily** responsible for promoting Th1 cell differentiation?

Accepted Answer

Interleukin-12

Answer

Interleukin-10

Answer

Interleukin-4

Answer

Tumor necrosis factor-alpha

Question 23

Which of the following is a mechanism of cell-mediated cytotoxicity?

Accepted Answer

Release of perforin and granzymes

Answer

Antibody-dependent cell-mediated cytotoxicity

Answer

Opsonization

Question 24

Which type of immune response is **most effective** against intracellular pathogens?

Accepted Answer

Cell-mediated immunity

Answer

Humoral immunity

Answer

Innate immunity

Answer

Passive immunity

Question 25

Which of the following is a characteristic of memory B cells?

Accepted Answer

Long-lived and rapidly activated upon re-exposure to antigen

Answer

Produce large amounts of antibodies upon first exposure to antigen

Answer

Are specific for multiple antigens

Question 26

Which organ is the **primary** site of B cell maturation?

Accepted Answer

Bone marrow

Answer

Thymus

Answer

Lymph nodes

Answer

Spleen

Question 27

Which cell type is responsible for **producing** antibodies?

Accepted Answer

B cells

Answer

Neutrophils

Answer

Macrophages

Answer

T cells