Semisolid Dosage Forms: Interactive Quizzes for Pharmacy Students

Question 1

Describe the fusion method for manufacturing ointments.

Accepted Answer

Gradually heat and mix ingredients until melted, then cool and stir while adding more ingredients

Answer

Dissolve ingredients in a solvent and evaporate the solvent

Answer

Mix all ingredients in a blender

Answer

Compress ingredients into a solid form

Question 2

Classify semisolid dosage forms into their three main categories, providing an example for each.

Accepted Answer

Ointments, creams, and gels

Answer

Powders, suspensions, and solutions

Answer

Capsules, tablets, and suppositories

Question 3

Which of the following ingredients is commonly used as a thickening agent in creams?

Accepted Answer

Stearic acid

Answer

Glycerin

Answer

Propylene glycol

Answer

Polysorbate 80

Question 4

What is a key advantage of using a gel as a semisolid dosage form?

Accepted Answer

Rapid and enhanced drug absorption

Answer

Easy and precise application

Answer

High drug loading capacity

Answer

Extended shelf-life

Question 5

What is the primary role of preservatives in semisolid dosage forms?

Accepted Answer

To prevent microbial contamination and extend shelf-life

Answer

To adjust pH and stability

Answer

To enhance drug absorption through the skin

Answer

To improve product texture and appearance

Question 6

Which of the following is a common excipient used to increase the viscosity of creams?

Accepted Answer

Carbomer

Answer

Cetrimide

Answer

Polyethylene glycol 400

Answer

Liquid paraffin

Question 7

What is the primary mechanism of drug release from semisolid dosage forms?

Accepted Answer

Diffusion across a concentration gradient

Answer

Osmosis through a semi-permeable membrane

Answer

Ion exchange with charged molecules

Answer

Chemical reaction with a catalyst

Question 8

What is the purpose of using a surfactant in semisolid dosage forms?

Accepted Answer

To reduce surface tension and improve spreadability

Answer

To increase viscosity and consistency

Answer

To inhibit microbial growth and extend shelf-life

Answer

To enhance drug absorption through the skin

Question 9

Which factors are the most important in determining how well drugs are absorbed from semisolid dosage forms?

Accepted Answer

Drug solubility, partitioning, and skin condition

Answer

Viscosity of the base and drug concentration

Answer

Manufacturing method and packaging material

Question 10

Which of the following is NOT a type of semisolid dosage form?

Accepted Answer

Suppositories

Answer

Ointments

Answer

Creams

Answer

Gels

Question 11

The primary purpose of an ointment base is to:

Accepted Answer

Deliver medication

Answer

Protect the wound

Answer

Provide a cooling effect

Answer

Emulsify ingredients

Question 12

The process of incorporating air into a cream to create a fluffy texture is known as:

Accepted Answer

Aeration

Answer

Emulsification

Answer

Homogenization

Answer

Dispersion

Question 13

Which test is used to determine the spreadability of an ointment?

Accepted Answer

Extrusion test

Answer

Penetration test

Answer

Disintegration test

Answer

Viscosity test

Question 14

The ideal pH range for most semisolid dosage forms is:

Accepted Answer

6-8

Answer

2-4

Answer

4-6

Answer

8-10

Question 15

The process of adding a liquid to a powdered base to create a smooth paste is called:

Accepted Answer

Trituration

Answer

Levigation

Answer

Incorporation

Answer

Granulation

Question 16

Which of the following is NOT a common semisolid dosage form?

Accepted Answer

Suspension

Answer

Ointment

Answer

Cream

Answer

Gel

Question 17

What is the primary function of an emulsifying agent in a cream?

Accepted Answer

To prevent phase separation of oil and water

Answer

To enhance drug absorption

Answer

To increase viscosity

Answer

To reduce skin irritation

Question 18

Which of the following is a key quality control parameter for ointments?

Accepted Answer

Consistency and homogeneity

Answer

pH

Answer

Dissolution rate

Answer

Sterility

Question 19

What is the purpose of a penetration enhancer in a topical gel?

Accepted Answer

To increase drug delivery through the skin

Answer

To reduce skin irritation

Answer

To improve stability

Answer

To enhance viscosity

Question 20

Which of the following is a common method for manufacturing semisolid dosage forms?

Accepted Answer

Extrusion

Answer

Tableting

Answer

Encapsulation

Answer

Lyophilization

Question 21

What is the role of a preservative in a semisolid dosage form?

Accepted Answer

To prevent microbial contamination

Answer

To enhance drug absorption

Answer

To increase stability

Answer

To reduce skin irritation

Question 22

Which of the following is a common excipient used in semisolid dosage forms to control viscosity?

Accepted Answer

Beeswax

Answer

Talc

Answer

Lactose

Answer

Starch

Question 23

What is the primary difference between an ointment and a cream?

Accepted Answer

Ointments have a higher oil content and are more occlusive

Answer

Creams are more viscous and spreadable

Answer

Ointments are easier to wash off

Answer

Creams are more likely to cause skin irritation