Adrenergic Drugs: Master Pharmacology with Interactive Quizzes

Question 1

Which of the following is NOT a mechanism of action of beta-adrenergic agonists?

Accepted Answer

Increase in intracellular calcium concentration

Answer

Activation of protein kinase A

Answer

Inhibition of phosphodiesterase

Answer

Stimulation of cardiac output

Question 2

Which of the following is a selective beta-1 adrenergic agonist?

Accepted Answer

Salmeterol

Answer

Epinephrine

Answer

Terazosin

Answer

Phenylephrine

Question 3

What is the primary mechanism of action of alpha-1 adrenergic antagonists?

Accepted Answer

Vasodilation

Answer

Bronchodilation

Answer

Uterine relaxation

Answer

Mydriasis

Question 4

Which of the following is a common adverse effect of beta-2 adrenergic agonists?

Accepted Answer

Tachycardia

Answer

Hypertension

Answer

Bradycardia

Answer

Hypotension

Question 5

What is the main clinical use of alpha-2 adrenergic agonists?

Accepted Answer

Prevention of premature labor

Answer

Treatment of hypertension

Answer

Relief of nasal congestion

Answer

Reversal of hypotension

Question 6

What is the mechanism of action of dobutamine?

Accepted Answer

Selective stimulation of beta-1 adrenergic receptors

Answer

Non-selective stimulation of alpha and beta adrenergic receptors

Answer

Selective stimulation of alpha-1 adrenergic receptors

Answer

Inhibition of phosphodiesterase

Question 7

What is the primary mechanism of action of labetalol?

Accepted Answer

Balanced alpha and beta adrenergic blockade

Answer

Selective beta-1 adrenergic blockade

Answer

Selective alpha-1 adrenergic blockade

Answer

Inhibition of calcium channels

Question 8

What is the mechanism of action of phenylephrine?

Accepted Answer

Stimulation of alpha-1 adrenergic receptors

Answer

Inhibition of beta-1 adrenergic receptors

Answer

Stimulation of beta-2 adrenergic receptors

Answer

Blockade of alpha-2 adrenergic receptors

Question 9

What is the main mechanism of action of alpha-2 adrenergic agonists?

Accepted Answer

Inhibition of norepinephrine release

Answer

Vasodilation

Answer

Bronchodilation

Answer

Sedation

Question 10

What is the first-line treatment for anaphylaxis?

Accepted Answer

Epinephrine

Answer

Salmeterol

Answer

Propranolol

Answer

Budesonide

Question 11

What is the mechanism of action of salbutamol?

Accepted Answer

Stimulation of beta-2 adrenergic receptors in bronchial smooth muscle

Answer

Inhibition of phosphodiesterase

Answer

Blockade of muscarinic receptors

Answer

Reduction of histamine release

Question 12

Which of the following is NOT a clinical use of alpha-1 adrenergic antagonists?

Accepted Answer

Asthma

Answer

Hypertension

Answer

BPH

Answer

Raynaud's disease

Question 13

What is the primary mechanism of action of dobutamine?

Accepted Answer

Stimulation of beta-1 adrenergic receptors

Answer

Inhibition of sodium-potassium ATPase

Answer

Blockade of calcium channels

Answer

Release of nitric oxide

Question 14

What is the primary mechanism of action of clonidine?

Accepted Answer

Stimulation of alpha-2 adrenergic receptors

Answer

Blockade of alpha-1 adrenergic receptors

Answer

Inhibition of dopamine reuptake

Answer

Activation of muscarinic receptors

Question 15

Which mechanism of action is NOT associated with alpha-1 adrenergic agonists?

Accepted Answer

Bronchial dilation

Answer

Vasoconstriction

Answer

Mydriasis

Answer

Uterine relaxation

Question 16

Which of the following is a selective beta-2 adrenergic agonist commonly used to treat asthma?

Accepted Answer

Salmeterol

Answer

Terazosin

Answer

Isoprenaline

Answer

Norepinephrine

Question 17

Which of the following physiological responses is primarily mediated by beta-1 adrenergic receptors?

Accepted Answer

Increased heart rate

Answer

Bronchial constriction

Answer

Uterine relaxation

Answer

Vasoconstriction

Question 18

Which of the following drugs is an alpha-2 adrenergic agonist used in the management of hypertension?

Accepted Answer

Clonidine

Answer

Terazosin

Answer

Phenylephrine

Answer

Propranolol

Question 19

Which of the following is a selective beta-1 adrenergic antagonist commonly used to treat angina?

Accepted Answer

Metoprolol

Answer

Albuterol

Answer

Phenylephrine

Answer

Terazosin

Question 20

Which of the following is NOT a physiological effect mediated by alpha-1 adrenergic receptors?

Accepted Answer

Bronchial smooth muscle relaxation

Answer

Increased heart rate

Answer

Mydriasis

Answer

Vasoconstriction

Question 21

The primary mechanism of action of beta-2 adrenergic agonists is to:

Accepted Answer

Stimulate adenylyl cyclase

Answer

Block voltage-gated calcium channels

Answer

Activate guanylyl cyclase

Answer

Inhibit phospholipase C

Question 22

Which of the following drugs is a non-selective alpha-adrenergic antagonist?

Accepted Answer

Phentolamine

Answer

Salmeterol

Answer

Dobutamine

Answer

Formoterol

Question 23

The use of beta-adrenergic blockers is contraindicated in patients with:

Accepted Answer

Asthma

Answer

Arrhythmias

Answer

Hypertension

Answer

Heart failure

Question 24

Which of the following is a potential adverse effect of alpha-1 adrenergic agonists?

Accepted Answer

Tachycardia

Answer

Hypotension

Answer

Bradycardia

Question 25

The therapeutic use of beta-adrenergic agonists includes:

Accepted Answer

Treatment of asthma

Answer

Treatment of angina

Answer

Treatment of bradycardia

Answer

Treatment of hypertension

Question 26

Which of the following drugs is a selective beta-1 adrenergic agonist?

Accepted Answer

Dobutamine

Answer

Propranolol

Answer

Salmeterol

Answer

Phenylephrine

Question 27

The use of alpha-2 adrenergic agonists is contraindicated in patients with:

Accepted Answer

Prostate enlargement

Answer

Arrhythmias

Answer

Hypertension

Answer

Asthma

Question 28

Which of the following is a potential adverse effect of beta-adrenergic antagonists?

Accepted Answer

Bradycardia

Answer

Tachycardia

Answer

Bronchospasm

Answer

Hypertension

Question 29

The therapeutic use of alpha-2 adrenergic antagonists includes:

Accepted Answer

Treatment of hypertension

Answer

Treatment of asthma

Answer

Treatment of angina

Answer

Treatment of bradycardia