Thyroid Medications: Comprehensive Learning Quizzes for Pharmacy Students

Question 1

Which hormone is primarily secreted by the thyroid gland?

Accepted Answer

Thyroxine

Answer

Estrogen

Answer

Progesterone

Answer

Insulin

Question 2

Which condition is an indication for thyroid hormone replacement therapy?

Accepted Answer

Hypothyroidism

Answer

Hyperthyroidism

Answer

Graves' disease

Answer

Hashimoto's thyroiditis

Question 3

How does propylthiouracil work?

Accepted Answer

Inhibits thyroid hormone synthesis

Answer

Stimulates thyroid hormone secretion

Answer

Inhibits thyroid hormone binding

Answer

Stimulates thyroid hormone release

Question 4

Which thyroid function test measures the amount of free thyroid hormone?

Accepted Answer

Free T4

Answer

T4

Answer

T3

Answer

TSH

Question 5

Which complication can result from untreated hypothyroidism?

Accepted Answer

Myxedema coma

Answer

Heart failure

Answer

Stroke

Answer

Kidney failure

Question 6

Which is the preferred initial treatment for hyperthyroidism due to Graves' disease?

Accepted Answer

Antithyroid medications

Answer

Radioactive iodine therapy

Answer

Surgery

Answer

Beta-blockers

Question 7

Which of the following drugs inhibits the production of thyroid hormones?

Accepted Answer

Methimazole

Answer

Iodine

Answer

Potassium iodide

Answer

Levothyroxine

Question 8

The primary mechanism of action of levothyroxine is to:

Accepted Answer

Enhance thyroid hormone receptor activity

Answer

Inhibit TSH release from the pituitary

Answer

Block peripheral conversion of T4 to T3

Answer

Promote iodine uptake by the thyroid gland

Question 9

Thiamazole primarily acts by inhibiting:

Accepted Answer

Thyroid peroxidase

Answer

Thyroglobulin

Answer

Sodium-iodide symporter

Answer

Thyroid hormone receptor

Question 10

A characteristic clinical manifestation of hypothyroidism is:

Accepted Answer

Constipation

Answer

Bradycardia

Answer

Weight loss

Answer

Increased body temperature

Question 11

To monitor the effectiveness of antithyroid drug therapy, which laboratory test is typically used?

Accepted Answer

Serum TSH

Answer

Serum T4

Answer

Serum T3

Answer

Thyroid antibody levels

Question 12

Levothyroxine, a thyroid hormone medication, acts by:

Accepted Answer

Replacing thyroid hormones

Answer

Inhibiting the secretion of thyroid-stimulating hormone (TSH)

Answer

Stimulating the production of thyroid hormones

Answer

Inactivating thyroid hormones at the periphery

Question 13

Carbimazole, an antithyroid medication, is primarily used for:

Accepted Answer

Treating hyperthyroidism

Answer

Treating hypothyroidism

Answer

Managing thyroid cancer

Answer

Reducing thyroid inflammation

Question 14

Which drug is generally not recommended for patients with untreated hyperthyroidism?

Accepted Answer

Amiodarone (an anti-arrhythmic)

Answer

Beta-blockers (e.g., propranolol)

Answer

Digoxin (used for heart conditions)

Answer

Lithium (used for bipolar disorder)

Question 15

The main mechanism of action of propylthiouracil, an antithyroid drug, is:

Accepted Answer

Inhibiting the enzyme thyroid peroxidase

Answer

Stimulating the secretion of thyroid hormones

Answer

Blocking thyroid hormone receptors

Answer

Replacing thyroid hormones

Question 16

What is the primary mechanism of action of thyroid hormones on cellular metabolism?

Accepted Answer

Inhibition of sodium-potassium ATPase

Answer

Activation of beta-adrenergic receptors

Answer

Inhibition of thyroid peroxidase

Answer

Stimulation of growth hormone secretion

Question 17

Which of the following medications can interact with levothyroxine and potentially reduce its absorption?

Accepted Answer

Omeprazole

Answer

Warfarin

Answer

Metformin

Answer

Aspirin

Question 18

What is the primary physiological effect of thyroid hormones on the body's metabolism?

Accepted Answer

Increased metabolic rate

Answer

Decreased cardiac output

Answer

Inhibition of muscle growth

Answer

Stimulation of gastric secretions

Question 19

Levothyroxine is a medication prescribed for hypothyroidism. What is its primary mechanism of action?

Accepted Answer

Levothyroxine is a synthetic form of T4, replacing the deficient thyroid hormone.

Answer

Levothyroxine stimulates the thyroid gland to produce more thyroid hormone.

Answer

Levothyroxine inhibits the thyroid gland from producing thyroid hormone.

Question 20

Propylthiouracil (PTU) is used to treat hyperthyroidism. Which of these is a potential adverse effect of PTU?

Accepted Answer

Agranulocytosis (a severe decrease in white blood cells)

Answer

Hypoglycemia (low blood sugar)

Answer

Constipation

Answer

Hypertension (high blood pressure)

Question 21

Radioactive iodine therapy is a treatment option for Graves' disease. Which of these is a contraindication for this therapy?

Accepted Answer

Pregnancy

Answer

Diabetes mellitus

Answer

Hypertension

Answer

Asthma

Question 22

A patient on levothyroxine for hypothyroidism requires regular monitoring. Which laboratory test is most important to assess the effectiveness of the treatment?

Accepted Answer

Thyroid stimulating hormone (TSH) level

Answer

Liver function tests (LFTs)

Answer

Complete blood count (CBC)

Answer

Renal function tests (RFTs)

Question 23

Which medication is commonly used to manage thyroid storm?

Accepted Answer

Propranolol (a beta-blocker)

Answer

Levothyroxine (a thyroid hormone replacement)

Answer

Radioactive iodine (used for long-term management)

Answer

Methimazole (an antithyroid drug)

Question 24

Methimazole is an antithyroid drug. What is its primary mechanism of action?

Accepted Answer

Inhibition of thyroid peroxidase, an enzyme crucial for thyroid hormone synthesis.

Answer

Stimulation of thyroid hormone synthesis.

Answer

Blocking the uptake of iodine by the thyroid gland.

Question 25

What is the effect of lithium on thyroid function?

Accepted Answer

Lithium can induce hypothyroidism (underactive thyroid).

Answer

Lithium is a preferred treatment for thyroid storm.

Answer

Lithium has no effect on thyroid function.

Answer

Lithium is effective in treating hyperthyroidism (overactive thyroid).

Question 26

Hashimoto's thyroiditis is an autoimmune disorder affecting the thyroid gland. Which statement is TRUE about this condition?

Accepted Answer

Hashimoto's thyroiditis is an autoimmune disorder.

Answer

Hashimoto's thyroiditis is always treated with surgery.

Answer

Hashimoto's thyroiditis is a rare condition.

Answer

Hashimoto's thyroiditis is caused by a viral infection.

Question 27

Long-term levothyroxine therapy can have potential adverse effects. Which of these is a possible consequence?

Accepted Answer

Osteoporosis (weakening of bones)

Answer

Constipation

Answer

Hypoglycemia

Answer

Hypertension

Question 28

Methimazole is used to treat hyperthyroidism. Which of these is a potential adverse effect?

Accepted Answer

Hepatotoxicity (damage to the liver)

Answer

Constipation

Answer

Hypoglycemia

Answer

Hypertension