Antiparasitic Agents and Resistance: Interactive Learning Quizzes

Question 1

Which of the following is NOT a typical mechanism of action of antiparasitic agents?

Accepted Answer

Stimulation of host antibody production

Answer

Inhibition of nucleic acid synthesis

Answer

Disruption of microtubule function

Answer

Inhibition of mitochondrial function

Question 2

Which antiparasitic agent inhibits protein synthesis by targeting the 80S ribosomes of parasites?

Accepted Answer

Paromomycin

Answer

Metronidazole

Answer

Albendazole

Answer

Clindamycin

Question 3

Which of the following infections is NOT treatable with antiparasitic agents?

Accepted Answer

Common cold

Answer

Malaria

Answer

Hookworm

Question 4

Which antiparasitic agent is effective against Plasmodium falciparum malaria, a species that has developed resistance to certain drugs?

Accepted Answer

Artemisinin-based combination therapy (ACT)

Answer

Chloroquine

Answer

Mefloquine

Answer

Primaquine

Question 5

Which class of antiparasitic agents targets microtubule function?

Accepted Answer

Benzimidazoles

Answer

Nitroimidazoles

Answer

Artemisinins

Answer

Antifolates

Question 6

What is a potential adverse effect associated with the antiparasitic agent pentamidine?

Accepted Answer

Neurotoxicity

Answer

Hepatotoxicity

Answer

Cardiotoxicity

Answer

Nephrotoxicity

Question 7

What is the current first-line treatment for uncomplicated falciparum malaria?

Accepted Answer

Artemisinin-based combination therapy (ACT)

Answer

Chloroquine

Answer

Mefloquine

Answer

Quinine

Question 8

What is the unique mechanism of action of metronidazole, an antiparasitic agent effective against anaerobic infections?

Accepted Answer

Generation of reactive oxygen species

Answer

Inhibition of protein synthesis

Answer

Disruption of membrane function

Answer

Inhibition of DNA synthesis

Question 9

Which of the following is NOT a mechanism by which parasites evade antiparasitic drugs?

Accepted Answer

Enhanced immune response

Answer

Altered drug target

Answer

Increased drug efflux

Answer

Elevated drug metabolism

Question 10

Which of the following parasitic diseases is primarily treated with primaquine?

Accepted Answer

Malaria

Answer

African trypanosomiasis

Answer

Leishmaniasis

Answer

Onchocerciasis

Question 11

Which of the following is a key characteristic of protozoan parasites that makes them susceptible to antifolates?

Accepted Answer

Presence of dihydrofolate reductase enzyme

Answer

Absence of cytochrome P450 enzymes

Answer

Rapid cell division rate

Answer

Lack of cell walls

Question 12

Which of the following is a common side effect associated with the use of metronidazole?

Accepted Answer

Nausea and vomiting

Answer

Neurotoxicity

Answer

Hepatotoxicity

Answer

Cardiac arrhythmias

Question 13

Which of the following is a major class of antiparasitic agents that targets parasite microtubules?

Accepted Answer

Benzimidazoles

Answer

Nitroimidazoles

Answer

Atovaquone

Answer

Artemisinin

Question 14

What is the primary mode of resistance to artemisinin in malaria parasites?

Accepted Answer

Target site mutations

Answer

Increased drug efflux

Answer

Overexpression of drug transporters

Answer

Altered drug metabolism

Question 15

Which of the following parasitic infections is caused by a protozoan parasite?

Accepted Answer

Malaria

Answer

Schistosomiasis

Answer

Lymphatic filariasis

Answer

Onchocerciasis

Question 16

What is the primary target of nitroimidazole antiparasitic drugs?

Accepted Answer

Parasite energy metabolism

Answer

Parasite DNA

Answer

Parasite proteins

Answer

Parasite cell wall

Question 17

Which of the following is NOT a mechanism of action of antiparasitic drugs?

Accepted Answer

Activation of the host immune response

Answer

Inhibition of nucleic acid synthesis

Answer

Disruption of membrane function

Answer

Inhibition of protein synthesis

Question 18

Which class of antiparasitic drugs targets the microtubules of parasites?

Accepted Answer

Benzimidazoles

Answer

Quinolones

Answer

Nitroimidazoles

Answer

Antifolates

Question 19

Which of the following is a clinical application of antiparasitic drugs?

Accepted Answer

Treatment of malaria

Answer

Treatment of cancer

Answer

Treatment of viral infections

Answer

Treatment of bacterial infections

Question 20

Which of the following is an example of a parasitic infection that can be treated with antiparasitic drugs?

Accepted Answer

Giardiasis

Answer

Influenza

Answer

Streptococcal pharyngitis

Answer

Tuberculosis

Question 21

What is the recommended course of action when a patient fails to respond to initial antiparasitic therapy?

Accepted Answer

Switch to an alternative drug class

Answer

Add an additional antiparasitic drug from the same class

Answer

Increase the dosage of the current drug

Answer

Discontinue antiparasitic treatment

Question 22

Which of the following is a mechanism of action of metronidazole against protozoa?

Accepted Answer

Disrupts DNA synthesis by damaging DNA

Answer

Inhibits cell wall synthesis

Answer

Inhibits folate synthesis

Answer

Inhibits protein synthesis

Question 23

Which of the following classes of antiparasitic agents is typically used to treat trypanosomiasis?

Accepted Answer

Nitroimidazoles

Answer

Benzimidazoles

Answer

Antifungals

Answer

Antibacterials

Question 24

Which of the following is a mode of transmission of plasmodium?

Accepted Answer

Mosquito bite

Answer

Skin contact

Answer

Airborne transmission

Answer

Fecal-oral route

Question 25

Which of the following is a strategy for preventing the development of drug resistance in parasitic infections?

Accepted Answer

Using combination therapies

Answer

Administering drugs prophylactically

Answer

Reducing the frequency of drug administration

Answer

Increasing the dosage of medications