Histopathology Quizzes: Master Microscopic Tissue Examination

Question 1

In histopathology, what is the main purpose of fixatives?

Accepted Answer

Preserve tissue structure and morphology

Answer

Enhance tissue staining

Answer

Eliminate pathogens

Question 2

In histopathology, which ethical principle is paramount when acquiring informed consent for tissue sample handling?

Accepted Answer

Autonomy

Answer

Beneficence

Answer

Justice

Answer

Non-maleficence

Question 3

Which technique is NOT involved in the preparation of a tissue sample for histopathological examination?

Accepted Answer

Immunofluorescence

Answer

Fixation

Answer

Dehydration

Answer

Embedding

Question 4

Which type of microscope is primarily used to examine histopathological slides?

Accepted Answer

Light microscope

Answer

Electron microscope

Answer

Fluorescence microscope

Answer

Confocal microscope

Question 5

What is the primary function of a microtome in histopathology?

Accepted Answer

To cut thin sections of tissue

Answer

To embed tissue in paraffin wax

Answer

To stain tissue sections

Answer

To view tissue sections under a microscope

Question 6

Which of the following is NOT a typical step in the preparation of a tissue sample for histopathology?

Accepted Answer

Immunohistochemistry

Answer

Dissection

Answer

Fixation

Answer

Embedding

Question 7

Keratin pearls are a characteristic microscopic feature associated with which type of cancer?

Accepted Answer

Squamous cell carcinoma

Answer

Adenocarcinoma

Answer

Melanoma

Answer

Lymphoma

Question 8

The primary application of immunohistochemistry in histopathology is to:

Accepted Answer

Visualize the localization of specific proteins within tissues

Answer

Identify the presence of microorganisms

Answer

Determine the genetic makeup of a tumor

Answer

Quantify the number of cells in a tissue

Question 9

Tissue sections for histopathology are typically cut using a(n):

Accepted Answer

Microtome

Answer

Cryostat

Answer

Vibratome

Answer

Ultramicrotome

Question 10

Van Gieson stain is commonly used in histopathology to highlight which tissue component?

Accepted Answer

Collagen fibers

Answer

Elastic fibers

Answer

Basement membranes

Answer

Mucin

Question 11

The primary role of a pathologist in the diagnosis of diseases is to:

Accepted Answer

Examine and interpret tissue samples under a microscope

Answer

Perform biopsies and other medical procedures

Answer

Prescribe medications and treatments

Answer

Provide counseling and support to patients

Question 12

The main advantage of using frozen sections in histopathology is:

Accepted Answer

Rapid diagnosis of surgical specimens

Answer

More detailed visualization of tissues compared to paraffin sections

Answer

Ability to study the effects of drugs on tissues

Answer

Identification of microorganisms

Question 13

Which staining technique is commonly employed to visualize connective tissue fibers clearly?

Accepted Answer

Masson's trichrome

Answer

Hematoxylin and eosin

Answer

Periodic acid-Schiff

Answer

Alcian blue

Question 14

From the following biopsy types, which is commonly used to obtain a specimen from the gastrointestinal tract?

Accepted Answer

Endoscopic biopsy

Answer

Needle biopsy

Answer

Punch biopsy

Answer

Excisional biopsy

Question 15

Which microscopic feature is characteristic of squamous cell carcinoma?

Accepted Answer

Intercellular bridges

Answer

Pleomorphic nuclei

Answer

Nests of tumor cells

Answer

Anaplastic features

Question 16

In histopathology, which type of microscope is frequently utilized?

Accepted Answer

Light microscope

Answer

Electron microscope

Answer

Confocal microscope

Answer

Scanning probe microscope

Question 17

Which step is NOT involved in the preparation of tissue samples for histopathological examination?

Accepted Answer

Immunohistochemistry

Answer

Fixation

Answer

Embedding

Answer

Sectioning

Question 18

Which type of microscope is employed to examine thin tissue sections?

Accepted Answer

Light microscope

Answer

Electron microscope

Answer

Scanning probe microscope

Answer

Atomic force microscope

Question 19

Which staining technique is used to specifically visualize DNA in tissue samples?

Accepted Answer

Feulgen

Answer

Hematoxylin and eosin

Answer

Periodic acid-Schiff

Answer

Trichrome

Question 20

Which cell type is commonly encountered in inflammatory responses and can be observed in histopathological samples?

Accepted Answer

Neutrophil

Answer

Erythrocyte

Answer

Osteocyte

Answer

Hepatocyte

Question 21

Which of the following is a common underlying cause of tissue necrosis?

Accepted Answer

Ischemia

Answer

Hypertrophy

Answer

Hyperplasia

Answer

Dysplasia

Question 22

Which type of benign tumor is characterized by the abnormal formation of new blood vessels?

Accepted Answer

Hemangioma

Answer

Osteosarcoma

Answer

Melanoma

Answer

Neurofibroma

Question 23

Which type of cancer arises from epithelial tissue?

Accepted Answer

Carcinoma

Answer

Sarcoma

Answer

Lymphoma

Answer

Leukemia