Antianginal Drugs Pharmacology: Online Quizzes and Learning

Question 1

What is the primary mechanism by which nitrates alleviate angina?

Accepted Answer

Dilating coronary arteries and reducing preload

Answer

Blocking calcium channels in the heart

Answer

Increasing heart rate and contractility

Answer

Inhibiting platelet aggregation

Question 2

What is the principal mechanism by which nitrates exert their effects?

Accepted Answer

Inhibiting calcium influx into vascular smooth muscle

Answer

Stimulating beta-adrenergic receptors

Answer

Blocking alpha-adrenergic receptors

Answer

Inhibiting angiotensin-converting enzyme

Question 3

Which of the following antianginal drugs is classified as a long-acting calcium channel blocker?

Accepted Answer

Amlodipine

Answer

Verapamil

Answer

Diltiazem

Answer

Nifedipine

Question 4

Which of the following patient groups would typically NOT receive antianginal medications as part of their treatment plan?

Accepted Answer

Patients with congestive heart failure

Answer

Patients with stable angina

Answer

Patients with unstable angina

Answer

Patients after myocardial infarction

Question 5

Which of the following is NOT a classification of antianginal medications?

Accepted Answer

Statins

Answer

Nitrates

Answer

Calcium channel blockers

Answer

Beta-blockers

Question 6

What is the primary therapeutic use of beta-blockers in the management of angina?

Accepted Answer

Reducing myocardial oxygen demand

Answer

Increasing coronary blood flow

Answer

Inhibiting platelet aggregation

Answer

Preventing thrombosis

Question 7

Which of the following drugs can potentially interact with nitrates, causing hypotension?

Accepted Answer

Sildenafil

Answer

Aspirin

Answer

Heparin

Answer

Warfarin

Question 8

What is the most frequent adverse effect associated with sublingual nitroglycerin?

Accepted Answer

Headache

Answer

Hypotension

Answer

Nausea

Answer

Tachycardia

Question 9

What is the primary goal of beta-blocker therapy in the treatment of angina?

Accepted Answer

To reduce heart rate and myocardial oxygen demand

Answer

To increase blood pressure and coronary blood flow

Answer

To prevent platelet aggregation and thrombosis

Answer

To dilate coronary arteries and improve myocardial perfusion

Question 10

The primary mechanism of action of most antianginal drugs is through:

Accepted Answer

Inhibition of calcium channels

Answer

Activation of beta-adrenergic receptors

Answer

Inhibition of angiotensin-converting enzyme

Answer

Antagonism of alpha-adrenergic receptors

Question 11

Ivabradine exerts its effect by:

Accepted Answer

Blocking the If current

Answer

Inhibiting the sodium-potassium pump

Answer

Activating the adenosine A1 receptor

Answer

Stimulating the sympathetic nervous system

Question 12

Which beta-blocker lacks selectivity for specific beta-adrenergic receptors?

Accepted Answer

Propranolol

Answer

Metoprolol

Answer

Atenolol

Answer

Bisoprolol

Question 13

Which of the following antianginal drugs acts directly on vascular smooth muscle to cause vasodilation?

Accepted Answer

Nitroglycerin

Answer

Atenolol

Answer

Diltiazem

Answer

Verapamil

Question 14

What is the primary mechanism by which beta-blockers reduce angina?

Accepted Answer

Reducing myocardial oxygen demand

Answer

Lowering heart rate

Answer

Increasing coronary blood flow

Answer

Improving ventricular contractility

Question 15

Which of the following adverse effects is commonly associated with dihydropyridine calcium channel blockers?

Accepted Answer

Peripheral edema

Answer

Bradycardia

Answer

Hypotension

Answer

Constipation

Question 16

What is the unique mechanism of action of ranolazine, a novel antianginal agent?

Accepted Answer

Inhibition of the late sodium current

Answer

Activation of adenosine receptors

Answer

Blockade of L-type calcium channels

Answer

Stimulation of guanylate cyclase

Question 17

Which of the following is an appropriate setting for the administration of intravenous nitroglycerin?

Accepted Answer

Acute myocardial infarction

Answer

Stable angina

Answer

Heart failure

Answer

Hypertension

Question 18

What is the main contraindication for the use of beta-blockers in the treatment of angina?

Accepted Answer

History of heart failure

Answer

Hyperthyroidism

Answer

Asthma

Answer

Diabetes mellitus

Question 19

What advantage does transdermal nitroglycerin patches offer over sublingual nitroglycerin?

Accepted Answer

Sustained and prolonged duration of action

Answer

Faster onset of action

Answer

Improved sublingual absorption

Answer

Lower risk of hypotension

Question 20

Which antianginal drug directly dilates coronary arteries?

Accepted Answer

Nitroglycerin

Answer

Verapamil

Answer

Diltiazem

Answer

Atenolol

Question 21

A patient with stable angina is prescribed a beta-blocker. How does this drug primarily help alleviate angina?

Accepted Answer

By reducing heart rate and contractility, decreasing myocardial oxygen demand

Answer

By increasing myocardial oxygen supply

Answer

By directly dilating coronary arteries

Question 22

What is a common adverse effect of nitrate therapy for angina?

Accepted Answer

Headache

Answer

Bronchospasm

Answer

Bradycardia

Question 23

Which calcium channel blocker is most commonly used for Prinzmetal's angina?

Accepted Answer

Nifedipine

Answer

Aspirin

Answer

Nitroglycerin

Answer

Metoprolol

Question 24

During an acute anginal episode, what is the most appropriate initial treatment?

Accepted Answer

Sublingual nitroglycerin

Answer

Oral calcium channel blocker

Answer

Intravenous beta-blocker

Answer

Aspirin

Question 25

A patient taking a long-acting nitrate for stable angina should be advised to do what to minimize tolerance?

Accepted Answer

Have a nitrate-free period each day

Answer

Avoid grapefruit juice

Answer

Take the medication on an empty stomach

Answer

Increase the dosage gradually

Question 26

Why is a combination of a beta-blocker and a calcium channel blocker sometimes prescribed for angina?

Accepted Answer

To achieve additive effects in reducing myocardial oxygen demand

Answer

To prevent the development of tolerance

Answer

To reduce the risk of adverse effects

Question 27

Which of the following is NOT a risk factor for developing angina?

Accepted Answer

Low cholesterol levels

Answer

Hypertension

Answer

Smoking

Answer

Diabetes mellitus