Liquid Dosage Forms: Master the Fundamentals for Pharmacists

Question 1

Which method is NOT used for mixing liquid dosage forms?

Accepted Answer

Centrifugation

Answer

Stirring

Answer

Homogenization

Answer

Sonication

Question 2

What is the primary role of suspending agents in suspensions?

Accepted Answer

To increase viscosity and prevent settling

Answer

To enhance dissolution rate

Answer

To act as preservatives

Answer

To provide a pleasant taste

Question 3

What is the main purpose of sterilization in the manufacture of liquid dosage forms?

Accepted Answer

To prevent microbial contamination

Answer

To increase shelf life

Answer

To improve solubility

Answer

To enhance absorption

Question 4

Which of the following is a quality control test for evaluating the physical stability of solutions?

Accepted Answer

Viscosity measurement

Answer

Particle size analysis

Answer

pH determination

Answer

Microbiological assay

Question 5

What is the primary advantage of using a homogenizer in the preparation of suspensions?

Accepted Answer

It reduces particle size and prevents sedimentation

Answer

It increases the viscosity of the suspension

Answer

It improves the solubility of the drug

Answer

It enhances the stability of the suspension

Question 6

Which of the following is NOT a type of gel used in pharmaceutical formulations?

Accepted Answer

Dry gel

Answer

Hydrogel

Answer

Oleogel

Answer

Emulgel

Question 7

What is the primary purpose of conducting a pH determination on a liquid dosage form?

Accepted Answer

To ensure the stability of the formulation

Answer

To determine the solubility of the drug

Answer

To evaluate the viscosity of the solution

Answer

To check for microbial contamination

Question 8

What is the primary purpose of a surfactant in an emulsion?

Accepted Answer

To reduce interfacial tension between oil and water

Answer

To increase viscosity

Answer

To enhance absorption

Answer

To prevent microbial growth

Question 9

What is the primary factor affecting the viscosity of a gel?

Accepted Answer

Polymer concentration

Answer

Temperature

Answer

pH

Answer

Ionic strength

Question 10

What is the role of a tonicity agent in a liquid dosage form?

Accepted Answer

To adjust the osmotic pressure

Answer

To enhance solubility

Answer

To increase viscosity

Answer

To prevent crystallization

Question 11

What is the purpose of a preservative in a liquid dosage form?

Accepted Answer

To prevent microbial growth

Answer

To adjust pH

Answer

To enhance absorption

Answer

To increase viscosity

Question 12

What is the primary mechanism of action of a sustained-release liquid dosage form?

Accepted Answer

Controlled release of active ingredient over time

Answer

Increased absorption

Answer

Reduced side effects

Answer

Improved patient compliance

Question 13

In a solution dosage form, which component is primarily responsible for inhibiting microbial growth?

Accepted Answer

Preservative

Answer

Buffer

Answer

Thickening agent

Answer

Antioxidant

Question 14

Which emulsion type is characterized by oil droplets dispersed within a continuous water phase?

Accepted Answer

Oil-in-water (O/W)

Answer

Water-in-oil (W/O)

Answer

Multiple

Answer

Inverted

Question 15

The process of dispersing liquid droplets into a gas is known as:

Accepted Answer

Aerosolization

Answer

Emulsification

Answer

Suspending

Question 16

Which method for preparing gels involves neutralizing polyacrylic acid with a base?

Accepted Answer

Ionotropic gelation

Answer

Polymerization

Answer

Cross-linking

Answer

Chemical reaction

Question 17

What is the primary purpose of incorporating thickening agents into liquid dosage forms?

Accepted Answer

To increase viscosity

Answer

To enhance bioavailability

Answer

To provide antimicrobial protection

Answer

To stabilize emulsions

Question 18

Which technique is commonly employed to determine the size distribution of particles in suspensions?

Accepted Answer

Light scattering

Answer

Chromatography

Answer

Microscopy

Answer

Electrophoresis

Question 19

What is the primary role of buffers in liquid dosage forms?

Accepted Answer

To maintain pH stability

Answer

To enhance drug solubility

Answer

To prevent microbial growth

Answer

To improve absorption

Question 20

Which of the following is not a type of liquid dosage form?

Accepted Answer

Tablet

Answer

Syrup

Answer

Emulsion

Answer

Suspension

Question 21

What is the fundamental difference between a solution and a suspension?

Accepted Answer

Dispersion state of the drug

Answer

Viscosity

Answer

Particle size

Answer

Stability

Question 22

Which of the following best describes a liquid dosage form containing a dissolved drug in water?

Accepted Answer

Aqueous solution

Answer

Suspension

Answer

Syrup

Answer

Emulsion

Question 23

What is the primary purpose of incorporating a solubilizer into a liquid formulation?

Accepted Answer

Enhance drug solubility

Answer

Extend shelf-life

Answer

Improve palatability

Answer

Increase viscosity

Question 24

Which of the following characterizes a suspension?

Accepted Answer

Solid drug particles dispersed in a liquid

Answer

A viscous liquid containing suspended drug particles

Answer

A dissolved drug in a liquid vehicle

Answer

Two immiscible liquids dispersed in each other

Question 25

What is dispersed in an emulsion?

Accepted Answer

Two immiscible liquids

Answer

A dissolved drug in a liquid

Answer

Solid particles in a liquid

Answer

Gas bubbles in a liquid

Question 26

Which agent is employed to stabilize emulsions?

Accepted Answer

Emulsifier

Answer

Sweetener

Answer

Preservative

Answer

Antioxidant

Question 27

What property characterizes a gel?

Accepted Answer

Semi-solid consistency due to a network of dispersed particles

Answer

Two immiscible liquids dispersed in each other

Answer

Solid drug particles dispersed in a liquid

Question 28

When can a liquid dosage form be considered sterile?

Accepted Answer

When it is devoid of viable microorganisms

Answer

When it is packaged in a tamper-proof container

Answer

When it has a palatable taste

Answer

When it is stable for a minimum of 2 years