Central Nervous System Pharmacology Quizzes - Master CNS Drug Actions

Question 1

Which combination of antidepressants increases the risk of developing serotonin syndrome?

Accepted Answer

Sertraline and venlafaxine

Answer

Fluoxetine and buspirone

Answer

Lithium and carbamazepine

Question 2

What mechanism of action do both selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs) share?

Accepted Answer

Inhibiting serotonin reuptake

Answer

Inhibiting norepinephrine reuptake

Answer

Blocking dopamine receptors

Answer

Enhancing GABA activity

Question 3

Which of the following antipsychotics is commonly used to treat schizophrenia?

Accepted Answer

Chlorpromazine

Answer

Fluoxetine

Answer

Buspirone

Answer

Valproic acid

Question 4

What is the primary adverse effect associated with the use of benzodiazepines?

Accepted Answer

Sedation

Answer

Tardive dyskinesia

Answer

Hypertension

Answer

Cardiovascular toxicity

Question 5

Which of the following is a distinguishing feature of atypical antipsychotics?

Accepted Answer

Increasing serotonin levels

Answer

Blocking dopamine D2 receptors

Answer

Inhibiting norepinephrine reuptake

Answer

Enhancing GABAergic transmission

Question 6

What is the main therapeutic benefit of using dopamine agonists in Parkinson's disease?

Accepted Answer

Reducing muscle rigidity

Answer

Improving cognitive function

Answer

Reversing the progression of the disease

Answer

Preventing the development of levodopa-induced dyskinesia

Question 7

What is the primary difference between the first- and second-generation antipsychotics?

Accepted Answer

Mechanism of action

Answer

Indication for use

Answer

Efficacy in treating positive symptoms

Answer

Cost of treatment

Question 8

Which of the following drugs acts as a partial agonist at dopamine D2 receptors?

Accepted Answer

Aripiprazole

Answer

Risperidone

Answer

Olanzapine

Answer

Chlorpromazine

Question 9

Which of the following is NOT a mechanism of action of selective serotonin reuptake inhibitors (SSRIs)?

Accepted Answer

Block serotonin receptors

Answer

Block serotonin reuptake

Answer

Stimulate serotonin release

Answer

Increase serotonin production

Question 10

Which neurotransmitter is NOT targeted by antidepressant drugs?

Accepted Answer

Acetylcholine

Answer

Serotonin

Answer

Norepinephrine

Answer

Dopamine

Question 11

Which antipsychotic medication is associated with a low risk of extrapyramidal symptoms?

Accepted Answer

Clozapine

Answer

Chlorpromazine

Answer

Haloperidol

Answer

Risperidone

Question 12

Which of the following anxiolytic drugs is NOT a benzodiazepine?

Accepted Answer

Propranolol

Answer

Buspirone

Answer

Alprazolam

Answer

Lorazepam

Question 13

Which adverse effect is commonly associated with antidepressant drugs?

Accepted Answer

Weight gain

Answer

Sedation

Answer

Tardive dyskinesia

Answer

Myocardial infarction

Question 14

What is the primary mechanism of action of most typical antipsychotics?

Accepted Answer

Dopamine D2 receptor blockade

Answer

Serotonin reuptake inhibition

Answer

GABA potentiation

Answer

Norepinephrine reuptake inhibition

Question 15

What is the primary function of GABA in the central nervous system?

Accepted Answer

Inhibitory neurotransmitter

Answer

Excitatory neurotransmitter

Answer

Neuromodulator

Answer

Hormone

Question 16

Which of the following drugs is a selective serotonin reuptake inhibitor (SSRI)?

Accepted Answer

Fluoxetine

Answer

Quetiapine

Answer

Tricyclic antidepressant

Answer

Phenelzine

Question 17

What is the primary indication for the prescription of anxiolytic drugs?

Accepted Answer

Anxiety disorders

Answer

Depression

Answer

Psychosis

Answer

Epilepsy

Question 18

What is the primary mechanism of action of benzodiazepines in treating anxiety disorders?

Accepted Answer

Enhance GABAergic neurotransmission

Answer

Inhibit GABAergic neurotransmission

Answer

Enhance glutamatergic neurotransmission

Answer

Enhance serotonergic neurotransmission

Question 19

Which of the following is NOT a common side effect associated with benzodiazepines?

Accepted Answer

Euphoria

Answer

Sedation

Answer

Ataxia

Answer

Cognitive impairment

Question 20

What is the main advantage of atypical antipsychotics compared to typical antipsychotics?

Accepted Answer

Lower risk of extrapyramidal side effects

Answer

Broader spectrum of antipsychotic activity

Answer

Faster onset of action

Answer

Lower risk of tardive dyskinesia

Question 21

Which of the following drugs acts as a positive allosteric modulator?

Accepted Answer

Benzodiazepines

Answer

Barbiturates

Answer

Phenytoin

Answer

Valproate

Question 22

What is the primary pharmacodynamic effect of GABA-ergic drugs?

Accepted Answer

Inhibition of neuronal firing

Answer

Stimulation of neuronal firing

Answer

Blockade of synaptic transmission

Answer

Enhancement of synaptic transmission

Question 23

What is the term used to describe the phenomenon where the effectiveness of a drug diminishes with repeated use?

Accepted Answer

Tolerance

Answer

Tachyphylaxis

Answer

Dependence

Answer

Addiction