Excipients in Drug Formulation: Interactive Learning Quizzes

Question 1

Within a solid oral dosage form, what is the primary function of a lubricant?

Accepted Answer

Reducing friction during compression

Answer

Enhancing powder flowability

Answer

Preventing powder caking

Answer

Extending tablet disintegration time

Question 2

Improved: Which type of excipient is primarily used to prevent the agglomeration of particles in a pharmaceutical formulation?

Accepted Answer

Improved: Dispersing agent

Answer

Improved: Emulsifying agent

Answer

Improved: Suspending agent

Answer

Improved: Glidant

Question 3

Improved: What is the main role of a lubricant in a pharmaceutical formulation?

Accepted Answer

Improved: Reduce friction during manufacturing

Answer

Improved: Enhance the absorption of the drug

Answer

Improved: Prevent caking

Answer

Improved: Improve the stability of the formulation

Question 4

Improved: Which of the following is a natural polymer commonly used as a thickening agent in pharmaceutical formulations?

Accepted Answer

Improved: Xanthan gum

Answer

Improved: Polyvinylpyrrolidone

Answer

Improved: Sodium lauryl sulfate

Answer

Improved: Magnesium stearate

Question 5

Improved: What is the primary purpose of using a chelating agent in a pharmaceutical formulation?

Accepted Answer

Improved: Prevent the precipitation of metal ions

Answer

Improved: Enhance the solubility of the drug

Answer

Improved: Reduce the toxicity of the formulation

Answer

Improved: Improve the stability of the active ingredient

Question 6

Improved: Which of the following excipients is primarily used to adjust the pH of a pharmaceutical formulation?

Accepted Answer

Improved: Buffering agent

Answer

Improved: Dispersing agent

Answer

Improved: Sorbent

Answer

Improved: Glidant

Question 7

Improved: What is the main function of an antioxidant in a pharmaceutical formulation?

Accepted Answer

Improved: Prevent oxidation of the active ingredient

Answer

Improved: Enhance the absorption of the drug

Answer

Improved: Reduce the toxicity of the formulation

Answer

Improved: Improve the stability of the excipients

Question 8

Improved: Which type of excipient is primarily used to control the release of the drug from a pharmaceutical formulation?

Accepted Answer

Improved: Release-modifying agent

Answer

Improved: Dispersing agent

Answer

Improved: Sorbent

Answer

Improved: Coating agent

Question 9

Improved: Which of the following is not a regulatory requirement for the use of excipients in pharmaceutical formulations?

Accepted Answer

Improved: They must enhance the therapeutic efficacy of the drug

Answer

Improved: They must be of pharmaceutical grade

Answer

Improved: They must be safe and non-toxic

Answer

Improved: They must be compatible with the other ingredients

Question 10

Which of the following is NOT a primary function of excipients in pharmaceutical formulations?

Accepted Answer

Alter the metabolism of the drug substance

Answer

Enhance drug solubility and bioavailability

Answer

Provide stability to the drug product

Answer

Facilitate drug manufacturing processes

Question 11

What is the primary purpose of excipients in a pharmaceutical formulation?

Accepted Answer

To enhance drug stability, effectiveness, and delivery

Answer

To minimize production and packaging costs

Answer

To modify drug absorption, distribution, metabolism, and excretion

Question 12

Excipient-drug interactions can impact drug efficacy or safety. Which interaction is a **potential concern** in this context?

Accepted Answer

Reduced drug stability

Answer

Enhanced drug solubility

Answer

Increased drug absorption

Question 13

Which excipient is primarily used to enhance the stability of a drug formulation against degradation?

Accepted Answer

Antioxidants

Answer

Sodium chloride

Answer

Sucrose

Answer

Gelatin

Question 14

What is the primary role of an antioxidant in a pharmaceutical formulation?

Accepted Answer

Prevent drug degradation

Answer

Enhance drug bioavailability

Answer

Increase drug solubility

Answer

Improve taste

Question 15

Identify the excipient used as a suspending agent in liquid formulations.

Accepted Answer

Methylcellulose

Answer

Sodium lauryl sulfate

Answer

Butylated hydroxyanisole (BHA)

Answer

Sodium chloride

Question 16

Which excipient is suitable for controlled drug release in a tablet containing a highly soluble drug?

Accepted Answer

Hydroxypropyl methylcellulose (HPMC)

Answer

Starch

Answer

Magnesium stearate

Answer

Talc

Question 17

What is the purpose of an anti-caking agent in a powder formulation?

Accepted Answer

Particle agglomeration

Answer

Moisture absorption

Answer

pH changes

Answer

Discoloration

Question 18

Which excipient is commonly used in topical formulations to enhance penetration?

Accepted Answer

Glycerin

Answer

Ascorbic acid

Answer

Magnesium sulfate

Answer

Sodium benzoate

Question 19

What is the primary function of a preservative in a pharmaceutical formulation?

Accepted Answer

Inhibit microbial growth

Answer

Increase drug solubility

Answer

Improve drug stability

Answer

Enhance bioavailability

Question 20

What is the primary aim of adding a chelating agent to a pharmaceutical formulation?

Accepted Answer

Inactivate heavy metal ions

Answer

Enhance drug solubility

Answer

Improve bioavailability

Answer

Prevent enzymatic degradation

Question 21

Binders are used in pharmaceutical formulations primarily to:

Accepted Answer

Hold ingredients together to form a cohesive mass

Answer

Enhance flowability

Answer

Protect drugs from degradation

Answer

Increase drug dissolution rate

Question 22

Which of the following excipients is commonly used as a glidant to improve powder flowability?

Accepted Answer

Colloidal silicon dioxide

Answer

Starch

Answer

Sodium chloride

Answer

Povidone

Question 23

Excipients that improve drug stability by preventing oxidation and other degradation pathways are known as:

Accepted Answer

Antioxidants

Answer

Preservatives

Answer

Buffering agents

Answer

Chelating agents

Question 24

Which of the following is a natural source of colorants used in pharmaceutical formulations?

Accepted Answer

Carmine

Answer

Indigo carmine

Answer

Sunset yellow

Answer

Tartrazine

Question 25

Excipients used to adjust and maintain the pH within a desired range in pharmaceutical formulations are:

Accepted Answer

Buffering agents

Answer

Antioxidants

Answer

Glidants

Answer

Surfactants

Question 26

Excipients that facilitate the dispersion or suspension of insoluble drug particles in liquid formulations are:

Accepted Answer

Suspending agents

Answer

Antioxidants

Answer

Binders

Answer

Glidants

Question 27

Which of the following is an example of a film-forming excipient used in coating tablets and other dosage forms?

Accepted Answer

Hydroxypropyl methylcellulose

Answer

Colloidal silicon dioxide

Answer

Lactose

Question 28

Excipients that are used to inhibit the growth of microorganisms in pharmaceutical formulations are:

Accepted Answer

Preservatives

Answer

Chelating agents

Answer

Antioxidants

Answer

Buffering agents