Basement Membrane and Cell Junctions: Interactive Learning Quizzes

Question 1

Which function is not associated with the basement membrane?

Accepted Answer

Transporting oxygen and glucose

Answer

Providing support and anchoring for epithelial cells

Answer

Acting as a selective filter and barrier

Answer

Facilitating cell signaling and communication

Question 2

Which of the following is a type of gap junction?

Accepted Answer

Connexin

Answer

Tight junction

Answer

Adherens junction

Answer

Desmoglein

Question 3

What is the main function of tight junctions?

Accepted Answer

To prevent leakage by sealing the intercellular space

Answer

To allow the unrestricted passage of substances between cells

Answer

To anchor cells to the extracellular matrix

Answer

To mediate cell-cell signaling

Question 4

Which collagen type is found in both the basement membrane and the extracellular matrix?

Accepted Answer

Type IV collagen

Answer

Type I collagen

Answer

Type II collagen

Answer

Type III collagen

Question 5

What is the role of integrins in cell-basement membrane interactions?

Accepted Answer

To bind to components of the basement membrane and facilitate cell attachment

Answer

To form tight junctions between cells

Answer

To connect cells to the actin cytoskeleton

Answer

To transport ions and molecules across cell membranes

Question 6

Which of the following cell junctions is asymmetric?

Accepted Answer

Desmosome

Answer

Tight junction

Answer

Adherens junction

Answer

Gap junction

Question 7

Which protein is responsible for anchoring epithelial cells to the basement membrane?

Accepted Answer

Integrin

Answer

Cadherin

Answer

Collagen

Answer

Laminin

Question 8

What is the primary function of desmosomes?

Accepted Answer

Anchoring intermediate filaments

Answer

Connecting epithelial cells to the underlying connective tissue

Answer

Forming a tight seal between adjacent epithelial cells

Answer

Facilitating the exchange of ions and nutrients

Question 9

Which of the following is not considered a type of cell junction?

Accepted Answer

Synapse

Answer

Adherens junction

Answer

Gap junction

Answer

Tight junction

Question 10

Which extracellular matrix protein is present in both the basement membrane and the extracellular matrix of connective tissues?

Accepted Answer

Collagen

Answer

Elastin

Answer

Fibronectin

Answer

Hyaluronic acid

Question 11

Which characteristic is associated with tight junctions?

Accepted Answer

Preventing the diffusion of solutes between cells

Answer

Permitting the passage of ions and small molecules

Answer

Fusing the membranes of adjacent cells

Answer

Being found exclusively in epithelia

Question 12

What is the primary role of the basement membrane?

Accepted Answer

Regulating the exchange of substances between the epithelium and the underlying connective tissue

Answer

Anchoring the epidermis to the dermis

Answer

Providing nutrients to the epithelium

Answer

Protecting the epithelium from mechanical damage

Question 13

Which technique is commonly used to investigate the structure of the basement membrane?

Accepted Answer

Transmission electron microscopy

Answer

Immunohistochemistry

Answer

X-ray crystallography

Answer

Magnetic resonance imaging

Question 14

Which glycoprotein located on the surface of epithelial cells interacts with integrins in the basement membrane?

Accepted Answer

Laminin

Answer

Collagen

Answer

Fibronectin

Answer

Cadherin

Question 15

Which type of cell junction is most likely to be present in tissues subjected to mechanical stress?

Accepted Answer

Desmosome

Answer

Adherens junction

Answer

Gap junction

Answer

Tight junction

Question 16

What condition is characterized by damage or absence of the basement membrane?

Accepted Answer

Epidermolysis bullosa

Answer

Pemphigus vulgaris

Answer

Dermatitis herpetiformis

Answer

Lichen planus

Question 17

Which component of the basement membrane primarily contributes to its tensile strength and provides a scaffold for cell attachment?

Accepted Answer

Type IV Collagen

Answer

Laminin

Answer

Proteoglycans

Answer

Fibronectin

Question 18

Tight junctions primarily serve to:

Accepted Answer

Prevent the passage of molecules between adjacent cells

Answer

Adhere cells together

Answer

Allow the exchange of ions and small molecules

Answer

Facilitate cell communication

Question 19

Which type of cell junction is characterized by a dense plaque on the cytoplasmic side and is anchored to intermediate filaments?

Accepted Answer

Desmosome

Answer

Adherens junction

Answer

Gap junction

Answer

Hemidesmosome

Question 20

The primary function of gap junctions is to:

Accepted Answer

Enable direct exchange of ions, nutrients, and signaling molecules between adjacent cells

Answer

Provide structural support for tissues

Answer

Regulate cell growth and differentiation

Answer

Facilitate cell movement

Question 21

Which of the following is NOT a component of the basement membrane?

Accepted Answer

Elastin

Answer

Laminin

Answer

Type VII Collagen

Answer

Glycoprotein

Question 22

Adherens junctions are linked to the cytoskeleton through:

Accepted Answer

Actin microfilaments

Answer

Intermediate filaments

Answer

Microtubules

Answer

Myosin filaments